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BMCBI
2011
14 years 6 months ago
The dChip survival analysis module for microarray data
Background: Genome-wide expression signatures are emerging as potential marker for overall survival and disease recurrence risk as evidenced by recent commercialization of gene ex...
Samir B. Amin, Parantu K. Shah, Aimin Yan, Sophia ...
EMO
2005
Springer
108views Optimization» more  EMO 2005»
15 years 5 months ago
Multi-objective Model Optimization for Inferring Gene Regulatory Networks
With the invention of microarray technology, researchers are able to measure the expression levels of ten thousands of genes in parallel at various time points of a biological proc...
Christian Spieth, Felix Streichert, Nora Speer, An...
BMCBI
2010
120views more  BMCBI 2010»
14 years 12 months ago
Examination of the relationship between essential genes in PPI network and hub proteins in reverse nearest neighbor topology
Background: In many protein-protein interaction (PPI) networks, densely connected hub proteins are more likely to be essential proteins. This is referred to as the "centralit...
Kang Ning, Hoong Kee Ng, Sriganesh Srihari, Hon Wa...
MICCAI
2010
Springer
14 years 10 months ago
Statistical Analysis of Structural Brain Connectivity
Abstract. We present a framework for statistical analysis in large cohorts of structural brain connectivity, derived from diffusion weighted MRI. A brain network is defined betwe...
Renske de Boer, Michiel Schaap, Fedde van der Lijn...
BMCBI
2010
84views more  BMCBI 2010»
14 years 12 months ago
Testing the additional predictive value of high-dimensional molecular data
Background: While high-dimensional molecular data such as microarray gene expression data have been used for disease outcome prediction or diagnosis purposes for about ten years i...
Anne-Laure Boulesteix, Torsten Hothorn