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BMCBI
2008
94views more  BMCBI 2008»
14 years 9 months ago
Conserved co-expression for candidate disease gene prioritization
Background: Genes that are co-expressed tend to be involved in the same biological process. However, co-expression is not a very reliable predictor of functional links between gen...
Martin Oti, Jeroen van Reeuwijk, Martijn A. Huynen...
IEEEVAST
2010
14 years 4 months ago
GeneTracer: Gene sequence analysis of disease mutations VAST 2010 mini challenge 3 award: Excellent process explanation
Our visual analytics tool GeneTracer, developed for the VAST 2010 genetic sequence mini challenge, visualizes gene sequences of current outbreaks and native sequences along with d...
Hanseung Lee, Jaegul Choo, Carsten Görg, Jaee...
BMCBI
2008
104views more  BMCBI 2008»
14 years 9 months ago
ExonMiner: Web service for analysis of GeneChip Exon array data
Background: Some splicing isoform-specific transcriptional regulations are related to disease. Therefore, detection of disease specific splice variations is the first step for fin...
Kazuyuki Numata, Ryo Yoshida, Masao Nagasaki, Ayum...
IJCBDD
2011
112views more  IJCBDD 2011»
14 years 4 months ago
A novel network model identified a 13-gene lung cancer prognostic signature
: This study presents a novel network methodology to identify prognostic gene signatures. Implication networks based on prediction logic are used to construct genome-wide coexpress...
Nancy Lan Guo, Ying-Wooi Wan, Swetha Bose, James D...
BMCBI
2010
135views more  BMCBI 2010»
14 years 9 months ago
Detecting disease associated modules and prioritizing active genes based on high throughput data
Background: The accumulation of high-throughput data greatly promotes computational investigation of gene function in the context of complex biological systems. However, a biologi...
Yu-Qing Qiu, Shi-Hua Zhang, Xiang-Sun Zhang, Luona...