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CSB
2003
IEEE
130views Bioinformatics» more  CSB 2003»
15 years 5 months ago
A Computational Approach to Reconstructing Gene Regulatory Networks
Reverse-engineering of gene networks using linear models often results in an underdetermined system because of excessive unknown parameters. In addition, the practical utility of ...
Xutao Deng, Hesham H. Ali
BMCBI
2011
14 years 3 months ago
Clustering gene expression data with a penalized graph-based metric
Background: The search for cluster structure in microarray datasets is a base problem for the so-called “-omic sciences”. A difficult problem in clustering is how to handle da...
Ariel E. Bayá, Pablo M. Granitto
JCB
2008
102views more  JCB 2008»
14 years 12 months ago
DUPCAR: Reconstructing Contiguous Ancestral Regions with Duplications
Accurately reconstructing the large-scale gene order in an ancestral genome is a critical step to better understand genome evolution. In this paper, we propose a heuristic algorit...
Jian Ma, Aakrosh Ratan, Brian J. Raney, Bernard B....
BIBE
2005
IEEE
15 years 5 months ago
Diagnostic Rules Induced by an Ensemble Method for Childhood Leukemia
We introduce a new ensemble method based on decision tree to discover significant and diversified rules for subtype classification of childhood acute lymphoblastic leukemia, a ...
Jinyan Li, Huiqing Liu, Ling Li
CBMS
2005
IEEE
15 years 5 months ago
An Online Analysis and Information Fusion Platform for Heterogeneous Biomedical Informatics Data
Current research in biomedical informatics involves analysis of multiple heterogeneous data sets. This includes patient demographics, clinical and pathology data, treatment histor...
Srivatsava Ranjit Ganta, Jyotsna Kasturi, John Gil...