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CEC
2008
IEEE
15 years 17 hour ago
Regulation of gene regulation - smooth binding with dynamic affinity affects evolvability
Abstract-- Understanding the evolvability of simple differentiating multicellular systems is a fundamental problem in the biology of genetic regulatory networks and in computationa...
Johannes F. Knabe, Chrystopher L. Nehaniv, Maria J...
ISBRA
2010
Springer
14 years 10 months ago
Analysis of Gene Interactions Using Restricted Boolean Networks and Time-Series Data
A popular model for gene regulatory networks is the Boolean network model. In this paper, we propose an algorithm to perform an analysis of gene regulatory interactions using the B...
Carlos H. A. Higa, Vitor H. P. Louzada, Ronaldo Fu...
HIPC
2003
Springer
15 years 5 months ago
Performance Analysis of Blue Gene/L Using Parallel Discrete Event Simulation
High performance computers currently under construction, such as IBM’s Blue Gene/L, consisting of large numbers (64K) of low cost processing elements with relatively small local...
Ed Upchurch, Paul L. Springer, Maciej Brodowicz, S...
BMCBI
2007
90views more  BMCBI 2007»
14 years 12 months ago
Gene network interconnectedness and the generalized topological overlap measure
Background: Network methods are increasingly used to represent the interactions of genes and/ or proteins. Genes or proteins that are directly linked may have a similar biological...
Andy M. Yip, Steve Horvath
CIKM
2009
Springer
15 years 6 months ago
Multivariate classification of urine metabolome profiles for breast cancer diagnosis
Background: Diagnosis techniques using urine are non-invasive, inexpensive, and easy to perform in clinical settings. The metabolites in urine, as the end products of cellular pro...
Younghoon Kim, Imhoi Koo, Byung Hwa Jung, Bong Chu...