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BMCBI
2008
90views more  BMCBI 2008»
14 years 9 months ago
Function2Gene: A gene selection tool to increase the power of genetic association studies by utilizing public databases and expe
Background: Many common disorders have multiple genetic components which convey increased susceptibility. SNPs have been used to identify genetic components which are associated w...
Don L. Armstrong, Chaim O. Jacob, Raphael Zidovetz...
JMLR
2010
85views more  JMLR 2010»
14 years 4 months ago
Matched Gene Selection and Committee Classifier for Molecular Classification of Heterogeneous Diseases
Microarray gene expressions provide new opportunities for molecular classification of heterogeneous diseases. Although various reported classification schemes show impressive perf...
Guoqiang Yu, Yuanjian Feng, David J. Miller, Jianh...
JAMIA
2011
94views more  JAMIA 2011»
14 years 11 days ago
Protein-network modeling of prostate cancer gene signatures reveals essential pathways in disease recurrence
Objective Uncovering the dominant molecular deregulation among the multitude of pathways implicated in aggressive prostate cancer is essential to intelligently developing targeted...
James L. Chen, Jianrong Li, Walter M. Stadler, Yve...
BMCBI
2006
171views more  BMCBI 2006»
14 years 9 months ago
The Autoimmune Disease Database: a dynamically compiled literature-derived database
Background: Autoimmune diseases are disorders caused by an immune response directed against the body's own organs, tissues and cells. In practice more than 80 clinically dist...
Thomas Karopka, Juliane Fluck, Heinz-Theodor Mevis...
BMCBI
2008
99views more  BMCBI 2008»
14 years 9 months ago
Exhaustive prediction of disease susceptibility to coding base changes in the human genome
Background: Single Nucleotide Polymorphisms (SNPs) are the most abundant form of genomic variation and can cause phenotypic differences between individuals, including diseases. Ba...
Vinayak Kulkarni, Mounir Errami, Robert Barber, Ha...