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BMCBI
2002
126views more  BMCBI 2002»
15 years 1 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
ICML
2009
IEEE
16 years 2 months ago
Group lasso with overlap and graph lasso
We propose a new penalty function which, when used as regularization for empirical risk minimization procedures, leads to sparse estimators. The support of the sparse vector is ty...
Laurent Jacob, Guillaume Obozinski, Jean-Philippe ...
PAKDD
2010
ACM
203views Data Mining» more  PAKDD 2010»
15 years 6 months ago
Finding Itemset-Sharing Patterns in a Large Itemset-Associated Graph
Both itemset mining and graph mining have been studied independently. Here, we introduce a novel data structure, which is an unweighted graph whose vertices contain itemsets. From ...
Mutsumi Fukuzaki, Mio Seki, Hisashi Kashima, Jun S...
BMCBI
2010
131views more  BMCBI 2010»
15 years 2 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
BMCBI
2008
128views more  BMCBI 2008»
15 years 2 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...