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BMCBI
2002
126views more  BMCBI 2002»
14 years 11 months ago
RIO: Analyzing proteomes by automated phylogenomics using resampled inference of orthologs
Background: When analyzing protein sequences using sequence similarity searches, orthologous sequences (that diverged by speciation) are more reliable predictors of a new protein&...
Christian M. Zmasek, Sean R. Eddy
ICML
2009
IEEE
16 years 19 days ago
Group lasso with overlap and graph lasso
We propose a new penalty function which, when used as regularization for empirical risk minimization procedures, leads to sparse estimators. The support of the sparse vector is ty...
Laurent Jacob, Guillaume Obozinski, Jean-Philippe ...
PAKDD
2010
ACM
203views Data Mining» more  PAKDD 2010»
15 years 4 months ago
Finding Itemset-Sharing Patterns in a Large Itemset-Associated Graph
Both itemset mining and graph mining have been studied independently. Here, we introduce a novel data structure, which is an unweighted graph whose vertices contain itemsets. From ...
Mutsumi Fukuzaki, Mio Seki, Hisashi Kashima, Jun S...
BMCBI
2010
131views more  BMCBI 2010»
14 years 12 months ago
JISTIC: Identification of Significant Targets in Cancer
Background: Cancer is caused through a multistep process, in which a succession of genetic changes, each conferring a competitive advantage for growth and proliferation, leads to ...
Felix Sanchez-Garcia, Uri David Akavia, Eyal Mozes...
BMCBI
2008
128views more  BMCBI 2008»
14 years 12 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...