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CPM
1999
Springer
129views Combinatorics» more  CPM 1999»
15 years 4 months ago
On the Structure of Syntenic Distance
This paper examines some of the rich structure of the syntenic distance model of evolutionary distance, introduced by Ferretti et al. (1996). The syntenic distance between two gen...
David Liben-Nowell
GECCO
2000
Springer
200views Optimization» more  GECCO 2000»
15 years 3 months ago
Chemical Crossover
During chemical reactions, molecules interact to produce new molecules. Some of the reaction mechanisms are very close to the way gene combine to produce new genes. Like the class...
Hugues Bersini
SNPD
2004
15 years 1 months ago
Prediction of Protein Dispensability through Integrated Analysis of Multiple-Source High-Throughput Data
Protein dispensability is fundamental to understanding of gene function and evolution. It is usually studied at the individual gene phenotype level. Recent advances in generating ...
Yu Chen, Dong Xu
BIOSYSTEMS
2007
175views more  BIOSYSTEMS 2007»
14 years 12 months ago
Alternative routes and mutational robustness in complex regulatory networks
Alternative pathways through a gene regulation network connect a regulatory molecule to its (indirect) regulatory target via different intermediate regulators. We here show for tw...
Andreas Wagner, Jeremiah Wright
JCB
2002
131views more  JCB 2002»
14 years 11 months ago
Modeling and Simulation of Genetic Regulatory Systems: A Literature Review
In order to understand the functioning of organisms on the molecular level, we need to know which genes are expressed, when and where in the organism, and to which extent. The reg...
Hidde de Jong