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BIOINFORMATICS
2008
172views more  BIOINFORMATICS 2008»
15 years 3 months ago
Fitting a geometric graph to a protein-protein interaction network
Motivation: Finding a good network null model for protein-protein interaction (PPI) networks is a fundamental issue. Such a model would provide insights into the interplay between...
Desmond J. Higham, Marija Rasajski, Natasa Przulj
166
Voted
BMCBI
2010
178views more  BMCBI 2010»
15 years 3 months ago
Selecting high-dimensional mixed graphical models using minimal AIC or BIC forests
Background: Chow and Liu showed that the maximum likelihood tree for multivariate discrete distributions may be found using a maximum weight spanning tree algorithm, for example K...
David Edwards, Gabriel C. G. de Abreu, Rodrigo Lab...
171
Voted
BMCBI
2010
133views more  BMCBI 2010»
15 years 3 months ago
Consolidating metabolite identifiers to enable contextual and multi-platform metabolomics data analysis
Background: Analysis of data from high-throughput experiments depends on the availability of well-structured data that describe the assayed biomolecules. Procedures for obtaining ...
Henning Redestig, Miyako Kusano, Atsushi Fukushima...
136
Voted
BMCBI
2010
176views more  BMCBI 2010»
15 years 3 months ago
Bayesian statistical modelling of human protein interaction network incorporating protein disorder information
Background: We present a statistical method of analysis of biological networks based on the exponential random graph model, namely p2-model, as opposed to previous descriptive app...
Svetlana Bulashevska, Alla Bulashevska, Roland Eil...
113
Voted
BMCBI
2010
96views more  BMCBI 2010»
15 years 3 months ago
Incorporating gene co-expression network in identification of cancer prognosis markers
Background: Extensive biomedical studies have shown that clinical and environmental risk factors may not have sufficient predictive power for cancer prognosis. The development of ...
Shuangge Ma, Mingyu Shi, Yang Li, Danhui Yi, Ben-C...
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