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» Conservativity in Structured Ontologies
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SEMWEB
2009
Springer
15 years 6 months ago
Measuring the Structural Preservation of Semantic Hierarchy Alignment
We present a method to measure the amount of structural distortion carried by an alignment between two taxonomic cores of ontologies represented as semantic hierarchies. We present...
Cliff Joslyn, Patrick Paulson, Amanda White
BMCBI
2007
141views more  BMCBI 2007»
14 years 11 months ago
Reconstruction of human protein interolog network using evolutionary conserved network
Background: The recent increase in the use of high-throughput two-hybrid analysis has generated large quantities of data on protein interactions. Specifically, the availability of...
Tao-Wei Huang, Chung-Yen Lin, Cheng-Yan Kao
BMCBI
2005
126views more  BMCBI 2005»
14 years 11 months ago
GANN: Genetic algorithm neural networks for the detection of conserved combinations of features in DNA
Background: The multitude of motif detection algorithms developed to date have largely focused on the detection of patterns in primary sequence. Since sequence-dependent DNA struc...
Robert G. Beiko, Robert L. Charlebois
DLOG
2008
15 years 2 months ago
Checking DL-Lite Modularity with QBF Solvers
We show how the reasoning tasks of checking various versions of conservativity for the description logic DL-Litebool can be reduced to satisfiability of quantified Boolean formulas...
Roman Kontchakov, Vladislav Ryzhikov, Frank Wolter...
BMCBI
2010
128views more  BMCBI 2010»
14 years 11 months ago
Conserved residue clusters at protein-protein interfaces and their use in binding site identification
Background: Biological evolution conserves protein residues that are important for structure and function. Both protein stability and function often require a certain degree of st...
Mainak Guharoy, Pinak Chakrabarti