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» Constraining Software Evolution
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BMCBI
2007
118views more  BMCBI 2007»
14 years 10 months ago
A topological algorithm for identification of structural domains of proteins
Background: Identification of the structural domains of proteins is important for our understanding of the organizational principles and mechanisms of protein folding, and for ins...
Frank Emmert-Streib, Arcady R. Mushegian
BMCBI
2006
87views more  BMCBI 2006»
14 years 9 months ago
Phylogeny based discovery of regulatory elements
Background: Algorithms that locate evolutionarily conserved sequences have become powerful tools for finding functional DNA elements, including transcription factor binding sites;...
Jason Gertz, Justin C. Fay, Barak A. Cohen
BMCBI
2011
14 years 1 months ago
Detection of Lineage-Specific Evolutionary Changes among Primate Species
Background: Comparison of the human genome with other primates offers the opportunity to detect evolutionary events that created the diverse phenotypes among the primate species. ...
Mihaela Pertea, Geo Pertea, Steven L. Salzberg
WCRE
2009
IEEE
15 years 4 months ago
A Study of the Time Dependence of Code Changes
—Much of modern software development consists of building on older changes. Older periods provide the structure (e.g., functions and data types) on which changes in future period...
Omar Alam, Bram Adams, Ahmed E. Hassan
WETICE
2005
IEEE
15 years 3 months ago
Evaluation of an awareness distribution mechanism: A simulation approach
In distributed software engineering, the role of informal communication is frequently overlooked. Participants simply employ their own ad-hoc methods of informal communication. Co...
David Nutter, Cornelia Boldyreff