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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2006
159views more  BMCBI 2006»
15 years 12 days ago
MultiSeq: unifying sequence and structure data for evolutionary analysis
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...
Elijah Roberts, John Eargle, Dan Wright, Zaida Lut...
209
Voted
ICDE
2006
IEEE
178views Database» more  ICDE 2006»
16 years 1 months ago
Declarative Querying for Biological Sequences
The ongoing revolution in life sciences research is producing vast amounts of genetic and proteomic sequence data. Scientists want to pose increasingly complex queries on this dat...
Sandeep Tata, Jignesh M. Patel, James S. Friedman,...
120
Voted
BMCBI
2008
108views more  BMCBI 2008»
15 years 14 days ago
An analysis of the positional distribution of DNA motifs in promoter regions and its biological relevance
Background: Motif finding algorithms have developed in their ability to use computationally efficient methods to detect patterns in biological sequences. However the posterior cla...
Ana C. Casimiro, Susana Vinga, Ana T. Freitas, Arl...
BMCBI
2010
219views more  BMCBI 2010»
14 years 7 months ago
BiologicalNetworks 2.0 - an integrative view of genome biology data
Background: A significant problem in the study of mechanisms of an organism's development is the elucidation of interrelated factors which are making an impact on the differe...
Sergey Kozhenkov, Yulia Dubinina, Mayya Sedova, Am...
RECOMB
1999
Springer
15 years 4 months ago
Evolution of metabolisms: a new method for the comparison of metabolic pathways
The abundance of information provided by completely sequenced genomes de nes a starting point for new insights in the multilevel organization of organisms and their evolution. At ...
Christian V. Forst, Klaus Schulten