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» Constraint Based Methods for Biological Sequence Analysis
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108
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BMCBI
2004
177views more  BMCBI 2004»
14 years 9 months ago
Gapped alignment of protein sequence motifs through Monte Carlo optimization of a hidden Markov model
Background: Certain protein families are highly conserved across distantly related organisms and belong to large and functionally diverse superfamilies. The patterns of conservati...
Andrew F. Neuwald, Jun S. Liu
91
Voted
RECOMB
2008
Springer
15 years 9 months ago
Integrating Sequence and Topology for Efficient and Accurate Detection of Horizontal Gene Transfer
Abstract. One phylogeny-based approach to horizontal gene transfer (HGT) detection entails comparing the topology of a gene tree to that of the species tree, and using their differ...
Cuong Than, Guohua Jin, Luay Nakhleh
BMCBI
2005
173views more  BMCBI 2005»
14 years 9 months ago
Phydbac "Gene Function Predictor" : a gene annotation tool based on genomic context analysis
Background: The large amount of completely sequenced genomes allows genomic context analysis to predict reliable functional associations between prokaryotic proteins. Major method...
François Enault, Karsten Suhre, Jean-Michel...
WABI
2009
Springer
117views Bioinformatics» more  WABI 2009»
15 years 4 months ago
A Simulation Study Comparing Supertree and Combined Analysis Methods Using SMIDGen
Background: Supertree methods comprise one approach to reconstructing large molecular phylogenies given multi-marker datasets: trees are estimated on each marker and then combined...
M. Shel Swenson, François Barbançon,...
RECOMB
2004
Springer
15 years 9 months ago
Multiple organism gene finding by collapsed gibbs sampling
The Gibbs sampling method has been widely used for sequence analysis after it was successfully applied to the problem of identifying regulatory motif sequences upstream of genes. ...
Sourav Chatterji, Lior Pachter