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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2006
92views more  BMCBI 2006»
14 years 9 months ago
Demonstration of two novel methods for predicting functional siRNA efficiency
Background: siRNAs are small RNAs that serve as sequence determinants during the gene silencing process called RNA interference (RNAi). It is well know that siRNA efficiency is cr...
Peilin Jia, Tieliu Shi, Yu-Dong Cai, Yixue Li
IJIT
2004
14 years 11 months ago
Computing Entropy for Ortholog Detection
Abstract-- Biological sequences from different species are called orthologs if they evolved from a sequence of a common ancestor species and they have the same biological function....
Hsing-Kuo Pao, John Case
BMCBI
2005
137views more  BMCBI 2005»
14 years 9 months ago
A configuration space of homologous proteins conserving mutual information and allowing a phylogeny inference based on pair-wise
Background: Popular methods to reconstruct molecular phylogenies are based on multiple sequence alignments, in which addition or removal of data may change the resulting tree topo...
Olivier Bastien, Philippe Ortet, Sylvaine Roy, Eri...
BMCBI
2004
196views more  BMCBI 2004»
14 years 9 months ago
MUSCLE: a multiple sequence alignment method with reduced time and space complexity
Background: In a previous paper, we introduced MUSCLE, a new program for creating multiple alignments of protein sequences, giving a brief summary of the algorithm and showing MUS...
Robert C. Edgar
70
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ISMB
1997
14 years 11 months ago
SEALS: A System for Easy Analysis of Lots of Sequences
We present a system of programs designed to facilitate sequence analysis projects involving large amounts of data. SEALS (System for Easy Analysis of Lots of Sequences) is a logic...
D. Roland Walker, Eugene V. Koonin