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» Constraint Based Methods for Biological Sequence Analysis
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BMCBI
2007
134views more  BMCBI 2007»
15 years 17 days ago
Efficient pairwise RNA structure prediction using probabilistic alignment constraints in Dynalign
Background: Joint alignment and secondary structure prediction of two RNA sequences can significantly improve the accuracy of the structural predictions. Methods addressing this p...
Arif Ozgun Harmanci, Gaurav Sharma, David H. Mathe...
CPAIOR
2010
Springer
15 years 3 months ago
Hybrid Methods for the Multileaf Collimator Sequencing Problem
Abstract. The multileaf collimator sequencing problem is an important component of the effective delivery of intensity modulated radiotherapy used in the treatment of cancer. The p...
Hadrien Cambazard, Eoin O'Mahony, Barry O'Sullivan
118
Voted
BMCBI
2007
147views more  BMCBI 2007»
15 years 17 days ago
Statistical significance of quantitative PCR
Background: PCR has the potential to detect and precisely quantify specific DNA sequences, but it is not yet often used as a fully quantitative method. A number of data collection...
Yann Karlen, Alan McNair, Sébastien Persegu...
73
Voted
RECOMB
2008
Springer
16 years 23 days ago
De Novo Sequencing of Nonribosomal Peptides
Abstract. While nonribosomal peptides (NRPs) are of tremendous pharmacological importance, there is currently no technology capable of highthroughput sequencing of NRPs. Difficulti...
Nuno Bandeira, Julio Ng, Dario Meluzzi, Roger G. L...
RECOMB
2010
Springer
15 years 2 months ago
naiveBayesCall: An Efficient Model-Based Base-Calling Algorithm for High-Throughput Sequencing
Immense amounts of raw instrument data (i.e., images of fluorescence) are currently being generated using ultra high-throughput sequencing platforms. An important computational cha...
Wei-Chun Kao, Yun S. Song