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» Constraint Based Methods for Biological Sequence Analysis
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99
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ICPP
2007
IEEE
15 years 6 months ago
Efficient Parallel Algorithm for Optimal Three-Sequences Alignment
Sequence alignment is a fundamental problem in the computational biology. Many alignment methods have been proposed in the literature, such as pair-wise sequence alignment (2SA), ...
Chun-Yuan Lin, Chen Tai Huang, Yeh-Ching Chung, Ch...
110
Voted
ISMB
1997
15 years 1 months ago
Functional Prediction of B. subtilis Genes from Their Regulatory Sequences
In bacterial cells, gene expression is regulated by multiple sigma factors, each of which has its promoter specificity, according to their conditions. Thus, if we can discriminate...
Tetsushi Yada, Yasushi Totoki, Takahiro Ishii, Ken...
JCB
2008
159views more  JCB 2008»
15 years 15 days ago
BayesMD: Flexible Biological Modeling for Motif Discovery
We present BayesMD, a Bayesian Motif Discovery model with several new features. Three different types of biological a priori knowledge are built into the framework in a modular fa...
Man-Hung Eric Tang, Anders Krogh, Ole Winther
101
Voted
CEC
2009
IEEE
15 years 5 months ago
A novel EDAs based method for HP model protein folding
— The protein structure prediction (PSP) problem is one of the most important problems in computational biology. This paper proposes a novel Estimation of Distribution Algorithms...
Benhui Chen, Long Li, Jinglu Hu
102
Voted
BMCBI
2005
190views more  BMCBI 2005»
15 years 13 days ago
Species-specific analysis of protein sequence motifs using mutual information
Background: Protein sequence motifs are by definition short fragments of conserved amino acids, often associated with a specific function. Accordingly protein sequence profiles de...
Jan Hummel, Nima Keshvari, Wolfram Weckwerth, Joac...