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» Constraint Based Methods for Biological Sequence Analysis
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RECOMB
2008
Springer
16 years 26 days ago
Reconstructing the Evolutionary History of Complex Human Gene Clusters
Abstract. Clusters of genes that evolved from single progenitors via repeated segmental duplications present significant challenges to the generation of a truly complete human geno...
Adam C. Siepel, Eric D. Green, Giltae Song, Tom&aa...
108
Voted
TMI
2008
149views more  TMI 2008»
15 years 13 days ago
Shape-Driven Three-Dimensional Watersnake Segmentation of Biological Membranes in Electron Tomography
Abstract--Due to the significant complexity of membrane morphology and the generally poor image quality in electron tomographic volumes, current automatic methods for segmentation ...
Hieu Tat Nguyen, Qiang Ji
106
Voted
BMCBI
2005
125views more  BMCBI 2005»
15 years 13 days ago
Multiple sequence alignments of partially coding nucleic acid sequences
Background: High quality sequence alignments of RNA and DNA sequences are an important prerequisite for the comparative analysis of genomic sequence data. Nucleic acid sequences, ...
Roman R. Stocsits, Ivo L. Hofacker, Claudia Fried,...
BMCBI
2010
156views more  BMCBI 2010»
15 years 20 days ago
Evaluation of statistical methods for normalization and differential expression in mRNA-Seq experiments
Background: High-throughput sequencing technologies, such as the Illumina Genome Analyzer, are powerful new tools for investigating a wide range of biological and medical question...
James H. Bullard, Elizabeth Purdom, Kasper D. Hans...
ALENEX
2003
137views Algorithms» more  ALENEX 2003»
15 years 1 months ago
The Markov Chain Simulation Method for Generating Connected Power Law Random Graphs
Graph models for real-world complex networks such as the Internet, the WWW and biological networks are necessary for analytic and simulation-based studies of network protocols, al...
Christos Gkantsidis, Milena Mihail, Ellen W. Zegur...