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» Constructing Information Bases Using Associative Structures
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ICML
2005
IEEE
16 years 5 months ago
Multi-class protein fold recognition using adaptive codes
We develop a novel multi-class classification method based on output codes for the problem of classifying a sequence of amino acids into one of many known protein structural class...
Eugene Ie, Jason Weston, William Stafford Noble, C...
BMCBI
2007
107views more  BMCBI 2007»
15 years 4 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
BMCBI
2008
86views more  BMCBI 2008»
15 years 4 months ago
Subfamily specific conservation profiles for proteins based on n-gram patterns
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
John K. Vries, Xiong Liu
BMCBI
2010
135views more  BMCBI 2010»
15 years 4 months ago
HDAPD: a web tool for searching the disease-associated protein structures
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Yi-Ruen Lin, Hsin-Yuan Wei, Tsung-Lin Tsai, Thy-Ho...
BMCBI
2007
182views more  BMCBI 2007»
15 years 4 months ago
Additive risk survival model with microarray data
Background: Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with ...
Shuangge Ma, Jian Huang