We develop a novel multi-class classification method based on output codes for the problem of classifying a sequence of amino acids into one of many known protein structural class...
Eugene Ie, Jason Weston, William Stafford Noble, C...
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Background: A new algorithm has been developed for generating conservation profiles that reflect the evolutionary history of the subfamily associated with a query sequence. It is ...
Background: The protein structures of the disease-associated proteins are important for proceeding with the structure-based drug design to against a particular disease. Up until n...
Background: Microarray techniques survey gene expressions on a global scale. Extensive biomedical studies have been designed to discover subsets of genes that are associated with ...