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» Constructing Optimal Highways
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138
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NIPS
1998
15 years 5 months ago
Finite-Sample Convergence Rates for Q-Learning and Indirect Algorithms
In this paper, we address two issues of long-standing interest in the reinforcement learning literature. First, what kinds of performance guarantees can be made for Q-learning aft...
Michael J. Kearns, Satinder P. Singh
151
Voted
WSC
1997
15 years 5 months ago
Covalidation of Dissimilarly Structured Models
A methodology is presented which allows comparison between models under different modeling paradigms. Consider the following situation: Two models have been constructed to study d...
Samuel A. Wright, Kenneth W. Bauer Jr.
164
Voted
BMCBI
2010
150views more  BMCBI 2010»
15 years 3 months ago
Systematic calibration of a cell signaling network model
Background: Mathematical modeling is being applied to increasingly complex biological systems and datasets; however, the process of analyzing and calibrating against experimental ...
Kyoung Ae Kim, Sabrina L. Spencer, John G. Albeck,...
133
Voted
BMCBI
2010
137views more  BMCBI 2010»
15 years 3 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
159
Voted
BMCBI
2008
228views more  BMCBI 2008»
15 years 3 months ago
Adaptive diffusion kernel learning from biological networks for protein function prediction
Background: Machine-learning tools have gained considerable attention during the last few years for analyzing biological networks for protein function prediction. Kernel methods a...
Liang Sun, Shuiwang Ji, Jieping Ye