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152
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ECAI
2010
Springer
15 years 4 months ago
On Semantic Update Operators for Answer-Set Programs
Logic programs under the stable models semantics, or answer-set programs, provide an expressive rule based knowledge representation framework, featuring formal, declarative and wel...
Martin Slota, João Leite
132
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BMCBI
2010
137views more  BMCBI 2010»
15 years 3 months ago
Improving pairwise sequence alignment accuracy using near-optimal protein sequence alignments
Background: While the pairwise alignments produced by sequence similarity searches are a powerful tool for identifying homologous proteins - proteins that share a common ancestor ...
Michael L. Sierk, Michael E. Smoot, Ellen J. Bass,...
121
Voted
BMCBI
2010
118views more  BMCBI 2010»
15 years 3 months ago
Artificial neural networks for the prediction of peptide drift time in ion mobility mass spectrometry
Background: There is an increasing usage of ion mobility-mass spectrometry (IMMS) in proteomics. IMMS combines the features of ion mobility spectrometry (IMS) and mass spectrometr...
Bing Wang, Steve Valentine, Manolo Plasencia, Srir...
BMCBI
2007
107views more  BMCBI 2007»
15 years 3 months ago
Prediction of potential drug targets based on simple sequence properties
Background: During the past decades, research and development in drug discovery have attracted much attention and efforts. However, only 324 drug targets are known for clinical dr...
Qingliang Li, Luhua Lai
151
Voted
BMCBI
2008
130views more  BMCBI 2008»
15 years 3 months ago
A novel series of compositionally biased substitution matrices for comparing Plasmodium proteins
Background: The most common substitution matrices currently used (BLOSUM and PAM) are based on protein sequences with average amino acid distributions, thus they do not represent ...
Kevin Brick, Elisabetta Pizzi
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