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AEI
2006
108views more  AEI 2006»
14 years 10 months ago
Grammatical rules for specifying information for automated product data modeling
This paper presents a linguistic framework for developing a formal knowledge acquisition method. The framework is intended to empower domain experts to specify information require...
Ghang Lee, Charles M. Eastman, Rafael Sacks, Shamk...
BMCBI
2006
205views more  BMCBI 2006»
14 years 10 months ago
Application of Petri net based analysis techniques to signal transduction pathways
Background: Signal transduction pathways are usually modelled using classical quantitative methods, which are based on ordinary differential equations (ODEs). However, some diffic...
Andrea Sackmann, Monika Heiner, Ina Koch
BMCBI
2006
144views more  BMCBI 2006»
14 years 10 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
BMCBI
2006
111views more  BMCBI 2006»
14 years 10 months ago
Tools for integrated sequence-structure analysis with UCSF Chimera
Background: Comparing related structures and viewing the structures in the context of sequence alignments are important tasks in protein structure-function research. While many pr...
Elaine C. Meng, Eric F. Pettersen, Gregory S. Couc...
BMCBI
2006
128views more  BMCBI 2006»
14 years 10 months ago
Rank-statistics based enrichment-site prediction algorithm developed for chromatin immunoprecipitation on chip experiments
Background: High density oligonucleotide tiling arrays are an effective and powerful platform for conducting unbiased genome-wide studies. The ab initio probe selection method emp...
Srinka Ghosh, Heather A. Hirsch, Edward A. Sekinge...
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