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» Contextual alignment of biological sequences
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101
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BMCBI
2005
158views more  BMCBI 2005»
15 years 10 days ago
Automated generation of heuristics for biological sequence comparison
Background: Exhaustive methods of sequence alignment are accurate but slow, whereas heuristic approaches run quickly, but their complexity makes them more difficult to implement. ...
Guy St. C. Slater, Ewan Birney
70
Voted
BICOB
2009
Springer
15 years 7 months ago
Multiple Sequence Alignment System for Pyrosequencing Reads
Fahad Saeed, Ashfaq A. Khokhar, Osvaldo Zagordi, N...
83
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ISMB
1998
15 years 1 months ago
Segment-Based Scores for Pairwise and Multiple Sequence Alignments
Burkhard Morgenstern, William R. Atchley, Klaus Ha...
114
Voted
TCBB
2008
120views more  TCBB 2008»
15 years 10 days ago
Learning Scoring Schemes for Sequence Alignment from Partial Examples
When aligning biological sequences, the choice of scoring scheme is critical. Even small changes in gap penalties, for example, can yield radically different alignments. A rigorous...
Eagu Kim, John D. Kececioglu
132
Voted
BIOCOMP
2006
15 years 1 months ago
PAC: Progressive Alignment with Consensus Sequences
Computation of multiple sequence alignments is one of the major open problems in computational molecular biology. The purpose of this study was to provide a new method, PAC (Progre...
Ke Liu, Mansur H. Samadzadeh