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JKM
2006
135views more  JKM 2006»
14 years 9 months ago
Learning from the Mars Rover Mission: scientific discovery, learning and memory
Purpose Knowledge management for space exploration is part of a multi-generational effort. Each mission builds on knowledge from prior missions, and learning is the first step in ...
Charlotte Linde
ASE
2005
124views more  ASE 2005»
14 years 9 months ago
Reuse-Conducive Development Environments
Despite its well-recognized benefits, software reuse has not met its expected success due to technical, cognitive, and social difficulties. We have systematically analyzed the reu...
Yunwen Ye, Gerhard Fischer
BMCBI
2005
162views more  BMCBI 2005»
14 years 9 months ago
Accelerated probabilistic inference of RNA structure evolution
Background: Pairwise stochastic context-free grammars (Pair SCFGs) are powerful tools for evolutionary analysis of RNA, including simultaneous RNA sequence alignment and secondary...
Ian Holmes
BMCBI
2005
106views more  BMCBI 2005»
14 years 9 months ago
SIMPROT: Using an empirically determined indel distribution in simulations of protein evolution
Background: General protein evolution models help determine the baseline expectations for the evolution of sequences, and they have been extensively useful in sequence analysis an...
Andy Pang, Andrew D. Smith, Paulo A. S. Nuin, Elis...
BMCBI
2005
152views more  BMCBI 2005»
14 years 9 months ago
Improved profile HMM performance by assessment of critical algorithmic features in SAM and HMMER
Background: Profile hidden Markov model (HMM) techniques are among the most powerful methods for protein homology detection. Yet, the critical features for successful modelling ar...
Markus Wistrand, Erik L. L. Sonnhammer
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