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» Continuous optimization methods for structure alignments
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BMCBI
2010
131views more  BMCBI 2010»
14 years 6 months ago
Dynamics based alignment of proteins: an alternative approach to quantify dynamic similarity
Background: The dynamic motions of many proteins are central to their function. It therefore follows that the dynamic requirements of a protein are evolutionary constrained. In or...
Márton Münz, Rune B. Lyngsø, Jo...
VLDB
2010
ACM
190views Database» more  VLDB 2010»
14 years 10 months ago
Continuous authentication on relational streams
According to the database outsourcing model, a data owner delegates database functionality to a thirdparty service provider, which answers queries received from clients. Authentic...
Stavros Papadopoulos, Yin Yang, Dimitris Papadias
BMCBI
2010
118views more  BMCBI 2010»
14 years 12 months ago
Towards realistic benchmarks for multiple alignments of non-coding sequences
Background: With the continued development of new computational tools for multiple sequence alignment, it is necessary today to develop benchmarks that aid the selection of the mo...
Jaebum Kim, Saurabh Sinha
BMCBI
2007
144views more  BMCBI 2007»
14 years 11 months ago
Assessing the ability of sequence-based methods to provide functional insight within membrane integral proteins: a case study an
Background: Efforts to predict functional sites from globular proteins is increasingly common; however, the most successful of these methods generally require structural insight. ...
Dennis R. Livesay, Patrick D. Kidd, Sepehr Eskanda...
BMCBI
2006
158views more  BMCBI 2006»
14 years 11 months ago
Detection of non-coding RNAs on the basis of predicted secondary structure formation free energy change
Background: Non-coding RNAs (ncRNAs) have a multitude of roles in the cell, many of which remain to be discovered. However, it is difficult to detect novel ncRNAs in biochemical s...
Andrew V. Uzilov, Joshua M. Keegan, David H. Mathe...