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» Continuous optimization methods for structure alignments
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98
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BMCBI
2010
116views more  BMCBI 2010»
15 years 2 months ago
Optimization algorithms for functional deimmunization of therapeutic proteins
Background: To develop protein therapeutics from exogenous sources, it is necessary to mitigate the risks of eliciting an anti-biotherapeutic immune response. A key aspect of the ...
Andrew S. Parker, Wei Zheng, Karl E. Griswold, Chr...
MICCAI
2002
Springer
16 years 2 months ago
Multi-modal Image Registration by Minimising Kullback-Leibler Distance
In this paper, we propose a multi-modal image registration method based on the a priori knowledge of the expected joint intensity distribution estimated from aligned training image...
Albert C. S. Chung, William M. Wells III, Alexande...
109
Voted
NHM
2010
87views more  NHM 2010»
14 years 8 months ago
The coolest path problem
We introduce the coolest path problem, which is a mixture of two well-known problems from distinct mathematical fields. One of them is the shortest path problem from combinatorial ...
Martin Frank, Armin Fügenschuh, Michael Herty...
ICIP
2008
IEEE
16 years 3 months ago
Articulated registration of 3D human geometry to X-ray image
A fully automatic 3D-2D articulated registration algorithm for aligning a whole-body human geometry to a 2D X-ray image is presented. Domain prior in the form of a hierarchical mo...
Sang N. Le, Jayashree Karlekar, Anthony C. Fang
GECCO
2010
Springer
148views Optimization» more  GECCO 2010»
15 years 6 months ago
Guarding against premature convergence while accelerating evolutionary search
The fundamental dichotomy in evolutionary algorithms is that between exploration and exploitation. Recently, several algorithms [8, 9, 14, 16, 17, 20] have been introduced that gu...
Josh C. Bongard, Gregory S. Hornby