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» Controlled Physical Random Functions
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99
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BMCBI
2010
139views more  BMCBI 2010»
14 years 10 months ago
A global optimization algorithm for protein surface alignment
Background: A relevant problem in drug design is the comparison and recognition of protein binding sites. Binding sites recognition is generally based on geometry often combined w...
Paola Bertolazzi, Concettina Guerra, Giampaolo Liu...
83
Voted
BMCBI
2008
107views more  BMCBI 2008»
14 years 10 months ago
Probe-specific mixed-model approach to detect copy number differences using multiplex ligation-dependent probe amplification (ML
Background: MLPA method is a potentially useful semi-quantitative method to detect copy number alterations in targeted regions. In this paper, we propose a method for the normaliz...
Juan R. González, Josep L. Carrasco, Llu&ia...
CORR
2010
Springer
182views Education» more  CORR 2010»
14 years 10 months ago
Fast Convergence of Natural Bargaining Dynamics in Exchange Networks
Bargaining networks model the behavior of a set of players who need to reach pairwise agreements for making profits. Nash bargaining solutions in this context correspond to soluti...
Yashodhan Kanoria, Mohsen Bayati, Christian Borgs,...
69
Voted
BMCBI
2006
86views more  BMCBI 2006»
14 years 10 months ago
The impact of sample imbalance on identifying differentially expressed genes
Background: Recently several statistical methods have been proposed to identify genes with differential expression between two conditions. However, very few studies consider the p...
Kun Yang, Jianzhong Li, Hong Gao
75
Voted
BMCBI
2006
137views more  BMCBI 2006»
14 years 10 months ago
Cell_motility: a cross-platform, open source application for the study of cell motion paths
Background: Migration is an important aspect of cellular behaviour and is therefore widely studied in cell biology. Numerous components are known to participate in this process in...
Lennart Martens, Geert Monsieur, Christophe Ampe, ...