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BMCBI
2008
128views more  BMCBI 2008»
14 years 10 months ago
Nonparametric relevance-shifted multiple testing procedures for the analysis of high-dimensional multivariate data with small sa
Background: In many research areas it is necessary to find differences between treatment groups with several variables. For example, studies of microarray data seek to find a sign...
Cornelia Frömke, Ludwig A. Hothorn, Siegfried...
BMCBI
2008
105views more  BMCBI 2008»
14 years 10 months ago
Using the longest significance run to estimate region-specific p-values in genetic association mapping studies
Background: Association testing is a powerful tool for identifying disease susceptibility genes underlying complex diseases. Technological advances have yielded a dramatic increas...
Ie-Bin Lian, Yi-Hsien Lin, Ying-Chao Lin, Hsin-Cho...
BMCBI
2007
103views more  BMCBI 2007»
14 years 10 months ago
A comprehensive evaluation of SAM, the SAM R-package and a simple modification to improve its performance
Background: The Significance Analysis of Microarrays (SAM) is a popular method for detecting significantly expressed genes and controlling the false discovery rate (FDR). Recently...
Shunpu Zhang
BMCBI
2008
94views more  BMCBI 2008»
14 years 10 months ago
Structural assembly of two-domain proteins by rigid-body docking
Background: Modelling proteins with multiple domains is one of the central challenges in Structural Biology. Although homology modelling has successfully been applied for predicti...
Tammy M. K. Cheng, Tom L. Blundell, Juan Fern&aacu...
CORR
2008
Springer
150views Education» more  CORR 2008»
14 years 10 months ago
Message-passing for Maximum Weight Independent Set
Abstract--In this paper, we investigate the use of messagepassing algorithms for the problem of finding the max-weight independent set (MWIS) in a graph. First, we study the perfor...
Sujay Sanghavi, Devavrat Shah, Alan S. Willsky