Sciweavers

114 search results - page 18 / 23
» Convergent algorithms for protein structural alignment
Sort
View
BMCBI
2008
145views more  BMCBI 2008»
15 years 14 days ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
JMLR
2006
115views more  JMLR 2006»
15 years 9 days ago
Structured Prediction, Dual Extragradient and Bregman Projections
We present a simple and scalable algorithm for maximum-margin estimation of structured output models, including an important class of Markov networks and combinatorial models. We ...
Benjamin Taskar, Simon Lacoste-Julien, Michael I. ...
101
Voted
ALMOB
2007
151views more  ALMOB 2007»
15 years 14 days ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
BMCBI
2007
102views more  BMCBI 2007»
15 years 14 days ago
A comprehensive system for evaluation of remote sequence similarity detection
Background: Accurate and sensitive performance evaluation is crucial for both effective development of better structure prediction methods based on sequence similarity, and for th...
Yuan Qi, Ruslan Sadreyev, Yong Wang, Bong-Hyun Kim...
BMCBI
2006
107views more  BMCBI 2006»
15 years 12 days ago
A reinforced merging methodology for mapping unique peptide motifs in members of protein families
Background: Members of a protein family often have highly conserved sequences; most of these sequences carry identical biological functions and possess similar three-dimensional (...
Hao-Teng Chang, Tun-Wen Pai, Tan-Chi Fan, Bo-Han S...