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BMCBI
2011
14 years 1 months ago
Evaluating methods for ranking differentially expressed genes applied to MicroArray Quality Control data
Background: Statistical methods for ranking differentially expressed genes (DEGs) from gene expression data should be evaluated with regard to high sensitivity, specificity, and r...
Koji Kadota, Kentaro Shimizu
BMCBI
2011
14 years 1 months ago
LAVA: An Open-Source Approach To Designing LAMP (Loop-Mediated Isothermal Amplification) DNA Signatures
Background: We developed an extendable open-source Loop-mediated isothermal AMPlification (LAMP) signature design program called LAVA (LAMP Assay Versatile Analysis). LAVA was cre...
Clinton Torres, Elizabeth A. Vitalis, Brian R. Bak...
BMCBI
2011
14 years 1 months ago
Smith-Waterman Peak Alignment for Comprehensive Two-dimensional Gas Chromatography Mass Spectrometry
Background: Comprehensive two-dimensional gas chromatography coupled with mass spectrometry (GC × GCMS) is a powerful technique which has gained increasing attention over the las...
Seongho Kim, Imhoi Koo, Aiqin Fang, Xiang Zhang
BMCBI
2011
14 years 1 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
BMCBI
2011
14 years 1 months ago
SeqGene: a comprehensive software solution for mining exome- and transcriptome- sequencing data
Background: The popularity of massively parallel exome and transcriptome sequencing projects demands new data mining tools with a comprehensive set of features to support a wide r...
Xutao Deng