We provide a method whereby, given mode and (upper approximation) type information, we can detect procedures and goals that can be guaranteed to not fail (i.e., to produce at leas...
3D parametric deformable models have been used to extract volumetric object boundaries and they generate smooth boundary surfaces as results. However, in some segmentation cases, ...
Tian Shen, Xiaolei Huang, Hongsheng Li, Edward Kim...
Abstract— Target shape design optimization problem (TSDOP) is a miniature model for real world design optimization problems. It is proposed as a test bed to design and analyze op...
Pan Zhang, Xin Yao, Lei Jia, Bernhard Sendhoff, Th...
We develop a variant of the Nelder-Mead (NM) simplex search procedure for stochastic simulation optimization that is designed to avoid many of the weaknesses encumbering such dire...
Background: The ability to design thermostable proteins is theoretically important and practically useful. Robust and accurate algorithms, however, remain elusive. One critical pr...