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BMCBI
2010
124views more  BMCBI 2010»
15 years 3 months ago
A factor model to analyze heterogeneity in gene expression
Background: Microarray technology allows the simultaneous analysis of thousands of genes within a single experiment. Significance analyses of transcriptomic data ignore the gene d...
Yuna Blum, Guillaume Le Mignon, Sandrine Lagarrigu...
150
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BMCBI
2007
112views more  BMCBI 2007»
15 years 3 months ago
Selecting dissimilar genes for multi-class classification, an application in cancer subtyping
Background: Gene expression microarray is a powerful technology for genetic profiling diseases and their associated treatments. Such a process involves a key step of biomarker ide...
Zhipeng Cai, Randy Goebel, Mohammad R. Salavatipou...
114
Voted
BMCBI
2005
122views more  BMCBI 2005»
15 years 3 months ago
FACT - a framework for the functional interpretation of high-throughput experiments
Background: Interpreting the results of high-throughput experiments, such as those obtained from DNA-microarrays, is an often time-consuming task due to the high number of data-po...
Felix Kokocinski, Nicolas Delhomme, Gunnar Wrobel,...
BMCBI
2005
121views more  BMCBI 2005»
15 years 3 months ago
Quality control and quality assessment of data from surface-enhanced laser desorption/ionization (SELDI) time-of flight (TOF) ma
Background: Proteomic profiling of complex biological mixtures by the ProteinChip technology of surfaceenhanced laser desorption/ionization time-of-flight (SELDI-TOF) mass spectro...
Huixiao Hong, Yvonne P. Dragan, Joshua Epstein, Ca...
136
Voted
OOPSLA
2010
Springer
15 years 1 months ago
An input-centric paradigm for program dynamic optimizations
Accurately predicting program behaviors (e.g., locality, dependency, method calling frequency) is fundamental for program optimizations and runtime adaptations. Despite decades of...
Kai Tian, Yunlian Jiang, Eddy Z. Zhang, Xipeng She...