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115
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BMCBI
2008
170views more  BMCBI 2008»
15 years 28 days ago
Evaluation of GO-based functional similarity measures using S. cerevisiae protein interaction and expression profile data
Background: Researchers interested in analysing the expression patterns of functionally related genes usually hope to improve the accuracy of their results beyond the boundaries o...
Tao Xu, LinFang Du, Yan Zhou
93
Voted
BMCBI
2006
119views more  BMCBI 2006»
15 years 26 days ago
Utilization of two sample t-test statistics from redundant probe sets to evaluate different probe set algorithms in GeneChip stu
Background: The choice of probe set algorithms for expression summary in a GeneChip study has a great impact on subsequent gene expression data analysis. Spiked-in cRNAs with know...
Zihua Hu, Gail R. Willsky
127
Voted
BMCBI
2006
213views more  BMCBI 2006»
15 years 26 days ago
CoXpress: differential co-expression in gene expression data
Background: Traditional methods of analysing gene expression data often include a statistical test to find differentially expressed genes, or use of a clustering algorithm to find...
Michael Watson
88
Voted
BMCBI
2007
141views more  BMCBI 2007»
15 years 25 days ago
On the origin and evolution of biosynthetic pathways: integrating microarray data with structure and organization of the Common
Background: The lysine, threonine, and methionine biosynthetic pathways share the three initial enzymatic steps, which are referred to as the Common Pathway (CP). In Escherichia c...
Marco Fondi, Matteo Brilli, Renato Fani
107
Voted
BMCBI
2004
114views more  BMCBI 2004»
15 years 21 days ago
Profiled support vector machines for antisense oligonucleotide efficacy prediction
Background: This paper presents the use of Support Vector Machines (SVMs) for prediction and analysis of antisense oligonucleotide (AO) efficacy. The collected database comprises ...
Gustavo Camps-Valls, Alistair M. Chalk, Antonio J....