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BMCBI
2010
152views more  BMCBI 2010»
14 years 9 months ago
Comparative study of three commonly used continuous deterministic methods for modeling gene regulation networks
Background: A gene-regulatory network (GRN) refers to DNA segments that interact through their RNA and protein products and thereby govern the rates at which genes are transcribed...
Martin T. Swain, Johannes J. Mandel, Werner Dubitz...
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BMCBI
2008
95views more  BMCBI 2008»
14 years 9 months ago
Identification and correction of abnormal, incomplete and mispredicted proteins in public databases
Background: Despite significant improvements in computational annotation of genomes, sequences of abnormal, incomplete or incorrectly predicted genes and proteins remain abundant ...
Alinda Nagy, Hédi Hegyi, Krisztina Farkas, ...
CANDC
2008
ACM
14 years 9 months ago
'Genome order index' should not be used for defining compositional constraints in nucleotide sequences
Background: The Z-curve is a three dimensional representation of DNA sequences proposed over a decade ago and has been extensively applied to sequence segmentation, horizontal gen...
Eran Elhaik, Dan Graur, Kresimir Josic
BMCBI
2007
151views more  BMCBI 2007»
14 years 9 months ago
Identification of hot regions in protein-protein interactions by sequential pattern mining
Background: Identification of protein interacting sites is an important task in computational molecular biology. As more and more protein sequences are deposited without available...
Chen-Ming Hsu, Chien-Yu Chen, Baw-Jhiune Liu, Chih...
SIGIR
2008
ACM
14 years 9 months ago
A unified and discriminative model for query refinement
This paper addresses the issue of query refinement, which involves reformulating ill-formed search queries in order to enhance relevance of search results. Query refinement typica...
Jiafeng Guo, Gu Xu, Hang Li, Xueqi Cheng