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ICECCS
1998
IEEE
168views Hardware» more  ICECCS 1998»
15 years 10 months ago
The Architecture Tradeoff Analysis Method
This paper presents the Architecture Tradeoff Analysis Method (ATAM), a structured technique for understanding the tradeoffs inherent in design. This method was developed to provi...
Rick Kazman, Mark H. Klein, Mario Barbacci, Thomas...
BMCBI
2006
192views more  BMCBI 2006»
15 years 6 months ago
Analysis of circular genome rearrangement by fusions, fissions and block-interchanges
Background: Analysis of genomes evolving via block-interchange events leads to a combinatorial problem of sorting by block-interchanges, which has been studied recently to evaluat...
Chin Lung Lu, Yen-Lin Huang, Tsui Ching Wang, Hsie...
BMCBI
2010
131views more  BMCBI 2010»
15 years 6 months ago
A comparison of approximation techniques for variance-based sensitivity analysis of biochemical reaction systems
Background: Sensitivity analysis is an indispensable tool for the analysis of complex systems. In a recent paper, we have introduced a thermodynamically consistent variance-based ...
Hong-Xuan Zhang, John Goutsias
BMCBI
2008
188views more  BMCBI 2008»
15 years 6 months ago
anNET: a tool for network-embedded thermodynamic analysis of quantitative metabolome data
Background: Compared to other omics techniques, quantitative metabolomics is still at its infancy. Complex sample preparation and analytical procedures render exact quantification...
Nicola Zamboni, Anne Kümmel, Matthias Heinema...
BMCBI
2008
110views more  BMCBI 2008»
15 years 6 months ago
Methylation Linear Discriminant Analysis (MLDA) for identifying differentially methylated CpG islands
Background: Hypermethylation of promoter CpG islands is strongly correlated to transcriptional gene silencing and epigenetic maintenance of the silenced state. As well as its role...
Wei Dai, Jens M. Teodoridis, Janet Graham, Constan...