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BMCBI
2011
14 years 3 months ago
Study of large and highly stratified population datasets by combining iterative pruning principal component analysis and STRUCTU
Background: The ever increasing sizes of population genetic datasets pose great challenges for population structure analysis. The Tracy-Widom (TW) statistical test is widely used ...
Tulaya Limpiti, Apichart Intarapanich, Anunchai As...
BMCBI
2011
14 years 3 months ago
FFCA: a feasibility-based method for flux coupling analysis of metabolic networks
Background: Flux coupling analysis (FCA) is a useful method for finding dependencies between fluxes of a metabolic network at steady-state. FCA classifies reactions into subsets (...
László Dávid, Sayed-Amir Mara...
BMCBI
2011
14 years 3 months ago
PhyloMap: an algorithm for visualizing relationships of large sequence data sets and its application to the influenza A virus ge
Background: Results of phylogenetic analysis are often visualized as phylogenetic trees. Such a tree can typically only include up to a few hundred sequences. When more than a few...
Jiajie Zhang, Amir Madany Mamlouk, Thomas Martinet...
BMCBI
2011
14 years 3 months ago
Cell Subset Prediction for Blood Genomic Studies
Background: Genome-wide transcriptional profiling of patient blood samples offers a powerful tool to investigate underlying disease mechanisms and personalized treatment decisions...
Christopher R. Bolen, Mohamed Uduman, Steven H. Kl...
BMCBI
2011
14 years 3 months ago
Predicting mutually exclusive spliced exons based on exon length, splice site and reading frame conservation, and exon sequence
Background: Alternative splicing of pre-mature RNA is an important process eukaryotes utilize to increase their repertoire of different protein products. Several types of differen...
Holger Pillmann, Klas Hatje, Florian Odronitz, Bjo...
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