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111
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BMCBI
2008
114views more  BMCBI 2008»
15 years 26 days ago
Partial mixture model for tight clustering of gene expression time-course
Background: Tight clustering arose recently from a desire to obtain tighter and potentially more informative clusters in gene expression studies. Scattered genes with relatively l...
Yinyin Yuan, Chang-Tsun Li, Roland Wilson
121
Voted
BMCBI
2006
130views more  BMCBI 2006»
15 years 24 days ago
An accurate and interpretable model for siRNA efficacy prediction
Background: The use of exogenous small interfering RNAs (siRNAs) for gene silencing has quickly become a widespread molecular tool providing a powerful means for gene functional s...
Jean-Philippe Vert, Nicolas Foveau, Christian Laja...
JCB
2008
90views more  JCB 2008»
15 years 22 days ago
A Simple Model of the Modular Structure of Transcriptional Regulation in Yeast
Resolving the general organizational principles that govern the interactions during transcriptional gene regulation has great relevance for understanding disease progression, biof...
Vladimir Filkov, Nameeta Shah
110
Voted
BRAIN
2010
Springer
14 years 11 months ago
Sparse Regression Models of Pain Perception
Discovering brain mechanisms underlying pain perception remains a challenging neuroscientific problem with important practical applications, such as developing better treatments f...
Irina Rish, Guillermo A. Cecchi, Marwan N. Baliki,...
102
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IGPL
2010
161views more  IGPL 2010»
14 years 11 months ago
Extending the Hegselmann-Krause Model I
Hegselmann and Krause have developed a simple yet powerful computational model for studying the opinion dynamics in societies of epistemically interacting truth-seeking agents. We...
Igor Douven, Alexander Riegler