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BMCBI
2007
104views more  BMCBI 2007»
13 years 6 months ago
Comparative evaluation of gene-set analysis methods
Background: Multiple data-analytic methods have been proposed for evaluating gene-expression levels in specific biological pathways, assessing differential expression associated w...
Qi Liu, Irina Dinu, Adeniyi J. Adewale, John D. Po...
BMCBI
2005
114views more  BMCBI 2005»
13 years 6 months ago
Signal transduction pathway profiling of individual tumor samples
Background: Signal transduction pathways convey information from the outside of the cell to transcription factors, which in turn regulate gene expression. Our objective is to anal...
Thomas Breslin, Morten Krogh, Carsten Peterson, Ca...
BMCBI
2006
146views more  BMCBI 2006»
13 years 6 months ago
Recursive gene selection based on maximum margin criterion: a comparison with SVM-RFE
Background: In class prediction problems using microarray data, gene selection is essential to improve the prediction accuracy and to identify potential marker genes for a disease...
Satoshi Niijima, Satoru Kuhara
BMCBI
2010
92views more  BMCBI 2010»
13 years 6 months ago
Integrating gene expression and GO classification for PCA by preclustering
Background: Gene expression data can be analyzed by summarizing groups of individual gene expression profiles based on GO annotation information. The mean expression profile per g...
Jorn R. de Haan, Ester Piek, René C. van Sc...
BMCBI
2008
157views more  BMCBI 2008»
13 years 6 months ago
Dimension reduction with redundant gene elimination for tumor classification
Background: Analysis of gene expression data for tumor classification is an important application of bioinformatics methods. But it is hard to analyse gene expression data from DN...
Xue-Qiang Zeng, Guo-Zheng Li, Jack Y. Yang, Mary Q...