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BMCBI
2007
139views more  BMCBI 2007»
14 years 12 months ago
Improving model predictions for RNA interference activities that use support vector machine regression by combining and filterin
Background: RNA interference (RNAi) is a naturally occurring phenomenon that results in the suppression of a target RNA sequence utilizing a variety of possible methods and pathwa...
Andrew S. Peek
BMCBI
2010
108views more  BMCBI 2010»
14 years 12 months ago
Predicting changes in protein thermostability brought about by single- or multi-site mutations
Background: An important aspect of protein design is the ability to predict changes in protein thermostability arising from single- or multi-site mutations. Protein thermostabilit...
Jian Tian, Ningfeng Wu, Xiaoyu Chu, Yunliu Fan
BMCBI
2010
133views more  BMCBI 2010»
14 years 12 months ago
Predicting enzyme targets for cancer drugs by profiling human Metabolic reactions in NCI-60 cell lines
Background: Drugs can influence the whole metabolic system by targeting enzymes which catalyze metabolic reactions. The existence of interactions between drugs and metabolic react...
Limin Li, Xiaobo Zhou, Wai-Ki Ching, Ping Wang
CGF
2008
141views more  CGF 2008»
14 years 12 months ago
Interactive Visualization of Multimodal Volume Data for Neurosurgical Tumor Treatment
Teaser Figure: Left: Brain, visualized using silhouettes, the lesion's spatial depth is displayed using a ring. Center: Combined rendering of brain tissue, skull and fiber tr...
Christian Rieder, Felix Ritter, Matthias Raspe, He...
BMCBI
2006
169views more  BMCBI 2006»
14 years 12 months ago
Comparative analysis of haplotype association mapping algorithms
Background: Finding the genetic causes of quantitative traits is a complex and difficult task. Classical methods for mapping quantitative trail loci (QTL) in miceuse an F2 cross b...
Phillip McClurg, Mathew T. Pletcher, Tim Wiltshire...