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BMCBI
2010
127views more  BMCBI 2010»
14 years 9 months ago
Computational prediction of type III secreted proteins from gram-negative bacteria
Background: Type III secretion system (T3SS) is a specialized protein delivery system in gramnegative bacteria that injects proteins (called effectors) directly into the eukaryoti...
Yang Yang, Jiayuan Zhao, Robyn L. Morgan, Wenbo Ma...
BMCBI
2008
117views more  BMCBI 2008»
14 years 9 months ago
A probabilistic framework to predict protein function from interaction data integrated with semantic knowledge
Background: The functional characterization of newly discovered proteins has been a challenge in the post-genomic era. Protein-protein interactions provide insights into the funct...
Young-Rae Cho, Lei Shi, Murali Ramanathan, Aidong ...
BMCBI
2008
145views more  BMCBI 2008»
14 years 9 months ago
Mapping gene expression quantitative trait loci by singular value decomposition and independent component analysis
Background: The combination of gene expression profiling with linkage analysis has become a powerful paradigm for mapping gene expression quantitative trait loci (eQTL). To date, ...
Shameek Biswas, John D. Storey, Joshua M. Akey
BMCBI
2008
152views more  BMCBI 2008»
14 years 9 months ago
JCoast - A biologist-centric software tool for data mining and comparison of prokaryotic (meta)genomes
Background: Current sequencing technologies give access to sequence information for genomes and metagenomes at a tremendous speed. Subsequent data processing is mainly performed b...
Michael Richter, Thierry Lombardot, Ivaylo Kostadi...
BMCBI
2007
105views more  BMCBI 2007»
14 years 9 months ago
VaxiJen: a server for prediction of protective antigens, tumour antigens and subunit vaccines
Background: Vaccine development in the post-genomic era often begins with the in silico screening of genome information, with the most probable protective antigens being predicted...
Irini A. Doytchinova, Darren R. Flower