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BMCBI
2011
14 years 1 months ago
Conotoxin Protein Classification Using Free Scores of Words and Support Vector Machines
Background: Conotoxin has been proven to be effective in drug design and could be used to treat various disorders such as schizophrenia, neuromuscular disorders and chronic pain. ...
Nazar Zaki, Stefan Wolfsheimer, Grégory Nue...
BMCBI
2010
100views more  BMCBI 2010»
14 years 7 months ago
New insights into protein-protein interaction data lead to increased estimates of the S. cerevisiae interactome size
Background: As protein interactions mediate most cellular mechanisms, protein-protein interaction networks are essential in the study of cellular processes. Consequently, several ...
Laure Sambourg, Nicolas Thierry-Mieg
KCAP
2009
ACM
15 years 4 months ago
Biomedical knowledge engineering tools based on experimental design: a case study based on neuroanatomical tract-tracing experim
Curating information from the literature for storage in databases is a crucial task in biological research, and many groups assign a particular person or team to that process. We ...
Gully A. P. C. Burns, Thomas A. Russ
BMCBI
2008
145views more  BMCBI 2008»
14 years 10 months ago
The contrasting properties of conservation and correlated phylogeny in protein functional residue prediction
Background: Amino acids responsible for structure, core function or specificity may be inferred from multiple protein sequence alignments where a limited set of residue types are ...
Jonathan R. Manning, Emily R. Jefferson, Geoffrey ...
BMCBI
2005
246views more  BMCBI 2005»
14 years 10 months ago
ParPEST: a pipeline for EST data analysis based on parallel computing
Background: Expressed Sequence Tags (ESTs) are short and error-prone DNA sequences generated from the 5' and 3' ends of randomly selected cDNA clones. They provide an im...
Nunzio D'Agostino, Mario Aversano, Maria Luisa Chi...