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BMCBI
2006
14 years 11 months ago
2006
Background: That the structure determines the function of proteins is a central paradigm in biology. However, protein functions are more directly related to cooperative effects at...
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BMCBI
2006
14 years 11 months ago
2006
Background: Restriction enzymes are one of the everyday tools used in molecular biology. The continuously expanding panel of known restriction enzymes (several thousands) renders ...
101
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BMCBI
2006
14 years 11 months ago
2006
Background: Microarray technology has become a widely accepted and standardized tool in biology. The first microarray data analysis programs were developed to support pair-wise co...
BMCBI
2006
14 years 11 months ago
2006
Background: Raw data normalization is a critical step in microarray data analysis because it directly affects data interpretation. Most of the normalization methods currently used...
100
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BMCBI
2006
14 years 11 months ago
2006
Background: Since the publication of the first draft of the human genome in 2000, bioinformatic data have been accumulating at an overwhelming pace. Currently, more than 3 million...