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» Current approaches to gene regulatory network modelling
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TFS
2010
152views Education» more  TFS 2010»
14 years 8 months ago
Robust Optimal Reference-Tracking Design Method for Stochastic Synthetic Biology Systems: T-S Fuzzy Approach
At present, the development in the nascent field of synthetic gene networks is still difficult. Most newly created gene networks are nonfunctioning due to intrinsic parameter fluct...
Bor-Sen Chen, Chih-Hung Wu
132
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BMCBI
2008
201views more  BMCBI 2008»
15 years 1 months ago
A copula method for modeling directional dependence of genes
Background: Genes interact with each other as basic building blocks of life, forming a complicated network. The relationship between groups of genes with different functions can b...
Jong-Min Kim, Yoon-Sung Jung, Engin A. Sungur, Kap...
BMCBI
2006
133views more  BMCBI 2006»
15 years 1 months ago
Topological basis of signal integration in the transcriptional-regulatory network of the yeast, Saccharomyces cerevisiae
Background: Signal recognition and information processing is a fundamental cellular function, which in part involves comprehensive transcriptional regulatory (TR) mechanisms carri...
Illés J. Farkas, Chuang Wu, Chakra Chennubh...
CMSB
2010
Springer
14 years 8 months ago
Action-based analysis of discrete regulatory networks with short-term stimuli
To incorporate instant effects and different timescales within a single biological system, an extension of discrete regulatory networks with short-term stimuli is proposed. By mai...
Christian Krause, Carola Krause, Erik P. de Vink
BMCBI
2010
183views more  BMCBI 2010»
14 years 11 months ago
The complexity of gene expression dynamics revealed by permutation entropy
Background: High complexity is considered a hallmark of living systems. Here we investigate the complexity of temporal gene expression patterns using the concept of Permutation En...
Xiaoliang Sun, Yong Zou, Victoria J. Nikiforova, J...