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» DNA Models and Algorithms for NP-Complete Problems
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JCB
2002
70views more  JCB 2002»
14 years 11 months ago
Strong Feature Sets from Small Samples
For small samples, classi er design algorithms typically suffer from over tting. Given a set of features, a classi er must be designed and its error estimated. For small samples, ...
Seungchan Kim, Edward R. Dougherty, Junior Barrera...
CIE
2007
Springer
15 years 5 months ago
Strict Self-assembly of Discrete Sierpinski Triangles
Winfree (1998) showed that discrete Sierpinski triangles can self-assemble in the Tile Assembly Model. A striking molecular realization of this self-assembly, using DNA tiles a fe...
James I. Lathrop, Jack H. Lutz, Scott M. Summers
BMCBI
2007
265views more  BMCBI 2007»
14 years 11 months ago
Large scale clustering of protein sequences with FORCE -A layout based heuristic for weighted cluster editing
Background: Detecting groups of functionally related proteins from their amino acid sequence alone has been a long-standing challenge in computational genome research. Several clu...
Tobias Wittkop, Jan Baumbach, Francisco P. Lobo, S...
BMCBI
2008
132views more  BMCBI 2008»
14 years 11 months ago
Clustering ionic flow blockade toggles with a Mixture of HMMs
Background: Ionic current blockade signal processing, for use in nanopore detection, offers a promising new way to analyze single molecule properties with potential implications f...
Alexander G. Churbanov, Stephen Winters-Hilt
BMCBI
2007
136views more  BMCBI 2007»
14 years 11 months ago
Prediction of tissue-specific cis-regulatory modules using Bayesian networks and regression trees
Background: In vertebrates, a large part of gene transcriptional regulation is operated by cisregulatory modules. These modules are believed to be regulating much of the tissue-sp...
Xiaoyu Chen, Mathieu Blanchette