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» DNA Sequence Design by Dynamic Neighborhood Searches
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BMCBI
2010
152views more  BMCBI 2010»
14 years 9 months ago
FITBAR: a web tool for the robust prediction of prokaryotic regulons
Background: The binding of regulatory proteins to their specific DNA targets determines the accurate expression of the neighboring genes. The in silico prediction of new binding s...
Jacques Oberto
BMCBI
2006
122views more  BMCBI 2006»
14 years 9 months ago
A multivariate prediction model for microarray cross-hybridization
Background: Expression microarray analysis is one of the most popular molecular diagnostic techniques in the post-genomic era. However, this technique faces the fundamental proble...
Yian A. Chen, Cheng-Chung Chou, Xinghua Lu, Elizab...
GECCO
2008
Springer
168views Optimization» more  GECCO 2008»
14 years 10 months ago
Parameterizing pair approximations for takeover dynamics
Pair approximations have often been used to predict equilibrium conditions in spatially-explicit epidemiological and ecological systems. In this work, we investigate whether this ...
Joshua L. Payne, Margaret J. Eppstein
CSB
2004
IEEE
123views Bioinformatics» more  CSB 2004»
15 years 1 months ago
A New Hardware Architecture for Genomic and Proteomic Sequence Alignment
We describe a novel hardware architecture for genomic and proteomic sequence alignment which achieves a speed-up of two to three orders of magnitude over Smith-Waterman dynamic pr...
Greg Knowles, Paul Gardner-Stephen
91
Voted
SODA
2010
ACM
426views Algorithms» more  SODA 2010»
15 years 6 months ago
Shape Replication Through Self-Assembly and RNase Enzymes
We introduce the problem of shape replication in the Wang tile self-assembly model. Given an input shape, we consider the problem of designing a self-assembly system which will re...
Zachary Abel, Nadia Benbernou, Mirela Damian, Erik...