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» DNA Sequence Design by Dynamic Neighborhood Searches
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ISMB
1994
14 years 10 months ago
An Improved System for Exon Recognition and Gene Modeling in Human DNA Sequence
A new version of the GRAIL system (Uberbacher and Mural, 1991; Mural et al., 1992; Uberbacher et al., 1993), called GRAILII, has recently been developed (Xu et al., 1994). GRAILII...
Yin Xu, J. Ralph Einstein, Richard J. Mural, Manes...
BIOCOMP
2008
14 years 11 months ago
Bioinformatics Tools: Searching for Markers in DNA/RNA Sequences
Research in bioinformatics and computational biology relies heavily on algorithms that facilitate the understanding of biological processes through the application of statistical ...
Kuha Mahalingam, Omar Bagasra
BMCBI
2002
120views more  BMCBI 2002»
14 years 9 months ago
tacg - a grep for DNA
Background: Pattern matching is the core of bioinformatics; it is used in database searching, restriction enzyme mapping, and finding open reading frames. It is done repeatedly ov...
Harry Mangalam
NAR
2006
84views more  NAR 2006»
14 years 9 months ago
Zinc Finger Tools: custom DNA-binding domains for transcription factors and nucleases
Individual zinc finger (ZF) domains that recognize DNA triplets with high specificity and affinity can be used to create designer transcription factors and nucleases that are spec...
Jeffrey G. Mandell, Carlos F. Barbas III
ASAP
2004
IEEE
124views Hardware» more  ASAP 2004»
15 years 1 months ago
Biosequence Similarity Search on the Mercury System
Biosequence similarity search is an important application in modern molecular biology. Search algorithms aim to identify sets of sequences whose extensional similarity suggests a c...
Praveen Krishnamurthy, Jeremy Buhler, Roger D. Cha...