Abstract— The DNA fragment assembly problem is to reconstruct a DNA chain from multiple fragments that have previously been sequenced in a laboratory. This is a critical step in ...
The problem addressed by this paper is accurate and automatic gene annotation following precise identification/annotation of exon and intron boundaries of biologically verified ...
Alexandre Tchourbanov, Daniel Quest, Hesham H. Ali...
Background: Unraveling the mechanisms that regulate gene expression is a major challenge in biology. An important task in this challenge is to identify regulatory elements, especi...
Background: ChIP-Seq, which combines chromatin immunoprecipitation (ChIP) with high-throughput massively parallel sequencing, is increasingly being used for identification of prot...
Congmao Wang, Jie Xu, Dasheng Zhang, Zoe A. Wilson...
The design of effective neighborhood structures is fundamentally important for creating better local search and metaheuristic algorithms for combinatorial optimization. Significant...