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» DNA Sequence Design by Dynamic Neighborhood Searches
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BMCBI
2008
211views more  BMCBI 2008»
14 years 9 months ago
CUDA compatible GPU cards as efficient hardware accelerators for Smith-Waterman sequence alignment
Background: Searching for similarities in protein and DNA databases has become a routine procedure in Molecular Biology. The Smith-Waterman algorithm has been available for more t...
Svetlin Manavski, Giorgio Valle
BMCBI
2006
144views more  BMCBI 2006»
14 years 9 months ago
methBLAST and methPrimerDB: web-tools for PCR based methylation analysis
Background: DNA methylation plays an important role in development and tumorigenesis by epigenetic modification and silencing of critical genes. The development of PCR-based methy...
Filip Pattyn, Jasmien Hoebeeck, Piet Robbrecht, Ev...
ISCAS
1994
IEEE
117views Hardware» more  ISCAS 1994»
15 years 1 months ago
Design of a Fast Sequential Decoding Algorithm Based on Dynamic Searching Strategy
This paper presents a new sequential decoding algorithm based on dynamic searching strategy to improve decoding efficiency. The searching strategy is to exploit both sorting and p...
Wen-Wei Yang, Li-Fu Jeng, Chen-Yi Lee
BMCBI
2006
129views more  BMCBI 2006»
14 years 9 months ago
EGenBio: A Data Management System for Evolutionary Genomics and Biodiversity
Background: Evolutionary genomics requires management and filtering of large numbers of diverse genomic sequences for accurate analysis and inference on evolutionary processes of ...
Laila A. Nahum, Matthew T. Reynolds, Zhengyuan O. ...
BMCBI
2007
233views more  BMCBI 2007»
14 years 9 months ago
160-fold acceleration of the Smith-Waterman algorithm using a field programmable gate array (FPGA)
Background: To infer homology and subsequently gene function, the Smith-Waterman (SW) algorithm is used to find the optimal local alignment between two sequences. When searching s...
Isaac T. S. Li, Warren Shum, Kevin Truong