Understanding how genetic variation affects the molecular function of gene products is an emergent area of bioinformatic research. Here, we present updates to MutDB (http://www.mu...
Arti Singh, Adebayo Olowoyeye, Peter H. Baenziger,...
We consider the following Tree-Constrained Bipartite Matching problem: Given two rooted trees T1 = (V1, E1), T2 = (V2, E2) and a weight function w : V1 × V2 → R+, find a maximu...
Stefan Canzar, Khaled M. Elbassioni, Gunnar W. Kla...
Background: Visualization of sequence annotation is a common feature in many bioinformatics tools. For many applications it is desirable to restrict the display of such annotation...
Background: Increasing amount of data from comparative genomics, and newly developed technologies producing accurate gene expression data facilitate the study of the expression di...
Xianjun Dong, Altuna Akalin, Yogita Sharma, Boris ...
Background: Genome-scale metabolic reconstructions under the Constraint Based Reconstruction and Analysis (COBRA) framework are valuable tools for analyzing the metabolic capabili...
Jan Schellenberger, Junyoung O. Park, Tom M. Conra...