Background: Many newly detected point mutations are located in protein-coding regions of the human genome. Knowledge of their effects on the protein's 3D structure provides i...
Hanka Venselaar, Tim A. H. te Beek, Remko K. P. Ku...
Background: A growing demand for tools to assist the building and analysis of biological networks exists in systems biology. We argue that the use of a formal approach is relevant...
m, modules, types and operations), different kinds of abstractions (functional/data, types/objects etc.) without falling into a loose collection of diagram languages. Considering a...
Background: Since its inception, proteomics has essentially operated in a discovery mode with the goal of identifying and quantifying the maximal number of proteins in a sample. I...
Mi-Youn K. Brusniak, Sung-Tat Kwok, Mark Christian...
Background: The identification of local similarities between two protein structures can provide clues of a common function. Many different methods exist for searching for similar ...