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BMCBI
2006
134views more  BMCBI 2006»
14 years 9 months ago
A statistical score for assessing the quality of multiple sequence alignments
Background: Multiple sequence alignment is the foundation of many important applications in bioinformatics that aim at detecting functionally important regions, predicting protein...
Virpi Ahola, Tero Aittokallio, Mauno Vihinen, Esa ...
BMCBI
2006
142views more  BMCBI 2006»
14 years 9 months ago
Correlated fragile site expression allows the identification of candidate fragile genes involved in immunity and associated with
Background: Common fragile sites (cfs) are specific regions in the human genome that are particularly prone to genomic instability under conditions of replicative stress. Several ...
Angela Re, Davide Corà, Alda Maria Puliti, ...
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BMCBI
2006
60views more  BMCBI 2006»
14 years 9 months ago
Use of a multi-way method to analyze the amino acid composition of a conserved group of orthologous proteins in prokaryotes
Background: Amino acids in proteins are not used equally. Some of the differences in the amino acid composition of proteins are between species (mainly due to nucleotide compositi...
Alberto Pasamontes, Santiago Garcia-Vallvé
BMCBI
2006
114views more  BMCBI 2006»
14 years 9 months ago
Impact of RNA structure on the prediction of donor and acceptor splice sites
Background: gene identification in genomic DNA sequences by computational methods has become an important task in bioinformatics and computational gene prediction tools are now es...
Sayed-Amir Marashi, Changiz Eslahchi, Hamid Pezesh...
BMCBI
2007
148views more  BMCBI 2007»
14 years 9 months ago
Blast sampling for structural and functional analyses
Background: The post-genomic era is characterised by a torrent of biological information flooding the public databases. As a direct consequence, similarity searches starting with ...
Anne Friedrich, Raymond Ripp, Nicolas Garnier, Emm...
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