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ALMOB
2008
124views more  ALMOB 2008»
15 years 3 months ago
A scoring matrix approach to detecting miRNA target sites
Background: Experimental identification of microRNA (miRNA) targets is a difficult and time consuming process. As a consequence several computational prediction methods have been ...
Simon Moxon, Vincent Moulton, Jan T. Kim
ALMOB
2007
151views more  ALMOB 2007»
15 years 3 months ago
Local sequence alignments statistics: deviations from Gumbel statistics in the rare-event tail
Background: The optimal score for ungapped local alignments of infinitely long random sequences is known to follow a Gumbel extreme value distribution. Less is known about the imp...
Stefan Wolfsheimer, Bernd Burghardt, Alexander K. ...
BMCBI
2010
112views more  BMCBI 2010»
15 years 3 months ago
Orientation-dependent backbone-only residue pair scoring functions for fixed backbone protein design
Background: Empirical scoring functions have proven useful in protein structure modeling. Most such scoring functions depend on protein side chain conformations. However, backbone...
Andrew J. Bordner
145
Voted
BMCBI
2010
154views more  BMCBI 2010»
15 years 3 months ago
LINNAEUS: A species name identification system for biomedical literature
Background: The task of recognizing and identifying species names in biomedical literature has recently been regarded as critical for a number of applications in text and data min...
Martin Gerner, Goran Nenadic, Casey M. Bergman
133
Voted
BMCBI
2010
155views more  BMCBI 2010»
15 years 3 months ago
FunctSNP: an R package to link SNPs to functional knowledge and dbAutoMaker: a suite of Perl scripts to build SNP databases
Background: Whole genome association studies using highly dense single nucleotide polymorphisms (SNPs) are a set of methods to identify DNA markers associated with variation in a ...
Stephen J. Goodswen, Cedric Gondro, Nathan S. Wats...
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